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(part 1) - Carbohydrates: monosaccharides (lecture 17), Chapter 8 ", - This PPT gives a view of medical colleges and infrastructural facilities established post year 2000, Glucose 2 ADP 2 NAD 2 Pi -----gt 2 Pyruvate, Binds on cells to IRS-1 (Insulin receptor, GIP-glucose dependent insulinotropic peptide, NOTE This is the reason the body has a better, Glut-4 skeletal muscle and adipose tissue, Glut-5 small intestine (Fructose Transport), Most monosaccharides can cross brush border but, glucose-6-phosphate (G6P)is the first reaction of, Four mammalian isozymes of hexokinase are known, Glucose-6-Phosphate to Fructose-6-Phosphate, Fructose-6-phosphate to Fructose-1,6-bisphosphate, Split of F-1,6-bisphosphate into dihydroxyacetone, 1,3-bisphosphoglycerate to 2,3-bisphosphoglycerate, 1,3-bisphosphoglycerate to 3-phosphoglycerate, 2-phosphoglycerate to phosphoenolpyruvate, May be caused hypoxia by reduced blood flow in, Ionic imbalance causing erythrocytes to swell, Hemolytic anemia-excessive RBC destruction, Above normal reticulocytes/total RBC ratio, Niacin, Riboflavin, ?-lipoic acid, Thiamine, CoA, For example NAD inhibits Protein Kinase which, ATP and Mg are necessary for Protein Kinase, Phosphoprotein Phosphatase removes phosphates, NOTE Ca concentration and ATP concentration, Catecholamines in cardiac muscle stimulates PDH, A glucocorticoid (Also anti-inflammatory), Stimulates Phenylethanolamine N-methyltransferase, Epinephrine secreted into blood and activates PDH, Carbon with three different groups therefore, Reactants to products favored (exergonic), Products to reactants favored (endergonic), Niacin, Riboflavin, Thiamine, ?-lipoic acid, Substrate level Phosphorylation NOT Oxidative, Slighty endergonic (Slightly favors malate, Contains tightly bound Tpp, lipoamide, FAD, Enzyme that catalyses coupled reaction is called, Involved in catabolic and anabolic processes, Aminotransferase Glutamate and ?-ketoglutarate, Aminotransferase Aspartate and Oxaloacetate, The aminotransferase associated with alanine and, Do NOT get confused with cyclooxygenase also, Genetic or acquired defect in coenzyme Q10, A cancer treatment in Mexico is called Amygdalin.

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